From: Intrapocket application of tea tree oil gel in the treatment of stage 2 periodontitis
 | Tests (n = 15) | Control (n = 15) | U | p |
---|---|---|---|---|
Gingival index | Â | Â | Â | Â |
Before | Â | Â | Â | Â |
 Mean ± SD | 1.17 ± 0.48 | 1.07 ± 0.36 | 93.0 | 0.436 |
 Median (Min.–Max.) | 1.25a (0.25–1.75) | 1.0a (0.75–2.0) |  |  |
3Â months | Â | Â | Â | Â |
 Mean ± SD | 0.27 ± 0.26 | 0.45 ± 0.40 | 84.50 | 0.250 |
 Median (Min.–Max.) | 0.25b (0.0–0.75) | 0.25b (0.0–1.50) |  |  |
6Â months | Â | Â | Â | Â |
 Mean ± SD | 0.03 ± 0.09 | 0.27 ± 0.20 | 40.0* | 0.002* |
 Median (Min.–Max.) | 0.0b (0.0–0.25) | 0.25b (0.0–0.50) |  |  |
p0 |  < 0.001* |  < 0.001* |  |  |
%Decrease after 3 m | 82.4 ± 16.4 | 60.3 ± 26.4 | 60.0* | 0.029* |
Decrease after 6 m | 1.1 ± 0.5 | 0.8 ± 0.3 | 62.0* | 0.037* |
%Decrease after 6 m | 97.9 ± 5.5 | 74.7 ± 19.7 | 34.0* | 0.001* |
Bleeding on Probing % | Â | Â | Â | Â |
Before | Â | Â | Â | Â |
  Mean ± SD | 81.7 ± 22.1 | 85 ± 12.7 | 111.0 | 0.967 |
 Median (Min.–Max.) | 75a (25–100) | 75a (75–100) |  |  |
3Â months | Â | Â | Â | Â |
 Mean ± SD | 26.7 ± 25.8 | 41.7 ± 32.3 | 84.50 | 0.250 |
 Median (Min.–Max.) | 25b (0–75) | 25b (0–100) |  |  |
6Â months | Â | Â | Â | Â |
 Mean ± SD | 3.3 ± 8.8 | 26.7 ± 20 | 40.0* | 0.002* |
 Median (Min.–Max.) | 0b (0–25) | 25b (0–50) |  |  |
p0 |  < 0.001* |  < 0.001* |  |  |
%Decrease after 3 m | 71.7 ± 27.2 | 52.2 ± 34.4 | 77.50 | 0.148 |
Decrease after 6 m | 78.3 ± 20.8 | 58.3 ± 20.4 | 54.0* | 0.015* |
%Decrease after 6 m | 96.7 ± 8.8 | 68.9 ± 23.2 | 36.0* | 0.001* |
Level of mmp8 (n/ml) | Â | Â | Â | Â |
Before | Â | Â | Â | Â |
 Mean ± SD | 2.6 ± 1.5 | 2 ± 1.6 | 91.0 | 0.389 |
 Median (Min.–Max.) | 2.3a (0.4–6.4) | 1.5a (0.4–6.2) |  |  |
1Â months | Â | Â | Â | Â |
 Mean ± SD | 1.7 ± 0.8 | 1.9 ± 2.4 | 91.0 | 0.389 |
 Median (Min.–Max.) | 1.8a (0.4–2.8) | 0.9b (0.3–9.7) |  |  |
3Â months | Â | Â | Â | Â |
 Mean ± SD | 0.6 ± 0.4 | 1 ± 0.7 | 83.50 | 0.233 |
 Median (Min.–Max.) | 0.5b (0.2–1.9) | 0.7b (0.3–2.8) |  |  |
6Â months | Â | Â | Â | Â |
 Mean ± SD | 0.3 ± 0.2 | 0.8 ± 0.6 | 46.0* | 0.005* |
 Median (Min.–Max.) | 0.2c (0.2–1.1) | 0.5c (0.2–2.6) |  |  |
p0 |  < 0.001* |  < 0.001* |  |  |
%Decrease after 3 m | 69.2 ± 23.4 | 44.3 ± 21.1 | 42.0* | 0.003* |
Decrease after 6 m | 2.3 ± 1.6 | 1.2 ± 1.1 | 62.0* | 0.037* |
%Decrease after 6 m | 82.8 ± 16.2 | 56.8 ± 19 | 27.0* |  < 0.001* |