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Table 3 Single nucleotide polymorphisms associated with ECC

From: Replication of GWAS significant loci in a sub-Saharan African Cohort with early childhood caries: a pilot study

Current study

Ballantine study

CHR

SNP

MAF (cases)

MAF (controls)

Minor allele

p

OR

L95

U95

OR

L95

U95

Minor allele

1

rs6702652

0.1632

0.1756

G

0.5384

0.92

0.69

1.21

0.26

0.48

0.14

G

4

rs3796983

0.3279

0.3414

G

0.5962

0.94

0.75

1.18

0.26

0.14

0.48

G

4

rs4690994

0.4347

0.4545

C

0.4591

0.92

0.75

1.14

3.5

2.09

5.95

C

5

rs1500131

0.1944

0.187

C

0.7267

1.05

0.80

1.37

3.53

2.09

5.95

C

9

rs1624327

0.405

0.3881

T

0.5201

1.07

0.86

1.33

2.91

1.79

4.73

T

10

rs932986

0.4718

0.4972

A

0.3461

0.90

0.73

1.18

2.83

1.76

4.55

A

10

rs11239282*

0.3531

0.3011

G

0.0397

1.27

1.01

1.59

2.91

1.8

4.73

G

11

rs12365282

0.2991

0.3324

A

0.1845

0.86

0.68

1.08

0.32

0.19

0.54

A

12

rs17104851

0.2887

0.2991

A

0.6707

0.95

0.75

1.20

5.54

2.53

12.1

A

12

rs7134614

0.2374

0.2131

C

0.2798

1.15

0.89

1.48

5.18

2.44

11

C

21

rs439888

0.2463

0.262

T

0.5019

0.92

0.72

1.17

3.6

2.1

6.2

T

22

rs7286697

0.4659

0.4618

C

0.8781

1.02

0.82

1.26

2.99

1.81

4.96

C

22

rs6000748

0.2959

0.3168

C

0.3998

0.91

0.72

1.14

3.87

2.09

7.19

C

22

rs131777*

0.4241

0.4801

C

0.0373

0.80

0.65

0.99

3.33

1.95

5.66

C

  1. MAF = Minor allele frequency * and Bold indicates SNPS with p < 0.05