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Table 1 Characteristics of the participants according to periodontitis status (n = 149)

From: S100A8 and S100A9 in saliva, blood and gingival crevicular fluid for screening established periodontitis: a cross-sectional study

Variable

NIPERIO (n = 50)

PERIO (n = 99)

p value

Clinical parametera, mean ± SD

   

Plaque index

0.94 ± 0.72

1.26 ± 1.03

0.033

Site with pocket depth ≥ 4 mm (%)

0.24 ± 0.80

14.67 ± 16.02

< 0.001

Bleeding site on probing (%)

60.26 ± 30.22

71.07 ± 25.80

0.025

Agea, mean ± SD

42.1 ± 15.1

55.8 ± 11.6

< 0.001

Sex, n(%)

  

0.005

Male

15 (30.0)

54 (54.5)

 

Female

35 (70.0)

45 (45.5)

 

Education, n(%)

  

0.054

Middle school

0 (0.00)

7 (7.1)

 

High school or higher

50 (100.0)

92 (92.9)

 

Smoking, n(%)b

  

0.262

No

48 (96.0)

90 (90.9)

 

Yes

2 (4.0)

9 (9.1)

 

Drinking, n(%)c

  

0.326

No

30 (60.0)

51 (51.5)

 

Yes

20 (40.0)

48 (48.5)

 

Diabetic, n(%)d

  

0.269

No

49 (98.0)

93 (93.9)

 

Yes

1 (2.0)

6 (7.0)

 

Hypercholesterolemiae, n(%)

  

0.102

No

49 (98.0)

90 (90.9)

 

Yes

1 (2.0)

9 (9.1)

 

Hypertensionf, n (%)

  

0.005

No

49 (98.0)

81 (81.8)

 

Yes

1 (2.0)

18 (18.2)

 

Obesityg, n (%)

  

0.031

No

40 (80.0)

62(62.6)

 

Yes

10 (20.0)

37 (37.4)

 
  1. Bold denotes statistical significance at p < 0.05
  2. PERIO stage II–IV periodontitis (AAP-EFP, 2018), NIPERIO No or stage I periodontitis
  3. p values: obtained by chi-square test for categorical variables and T-test for acontinuous variables. SD standard deviation
  4. bSmoking: No = never smoked, Yes = past and current smoker
  5. cAlcohol intake: No = never drunken, Yes = past and current drinker
  6. dDiabetic: Yes = fasting plasma glucose > 126 or taking diabetes medication
  7. eHypercholesterolemia: Yes = plasma cholesterol > 240 or taking hypercholesterolemia medication
  8. fHypertension: Yes = systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg or taking hypertension medication
  9. gObesity: Body mass index (body kg/height m2) ≥ 25