Fig. 5
From: RNAseq of TGF-β receptor type I kinase-dependent genes in oral fibroblast exposed to milk
D609 blocks IL11 in gingival fibroblasts exposed to milk. Gingival fibroblasts were exposed to 5% of an aqueous fraction of human milk (HM) with and without 40 µM D609 (A), an aqueous fraction of human milk (HM) with and without 200 nM calphostin C (B), sphingosine 1-phosphate 50 µM (C) an aqueous fraction of human milk (HM) with and without 10 µM sphingosine kinase 1 inhibitor (D) followed by RT-PCR. Statistical analysis of four independent experiments was based on a paired t-test