| Pathological differentiation degree of TSCC | |||||||
---|---|---|---|---|---|---|---|---|
Primary cohort | Test cohort | |||||||
Poorly differentiated (n = 23) | Moderately differentiated (n = 28) | Well differentiated (n = 21) | P-value | Poorly differentiated (n = 13) | Moderately differentiated (n = 20) | Well differentiated (n = 22) | P-value | |
Sex | ||||||||
 Male | 21 | 24 | 17 | 0.610 | 9 | 9 | 12 | 0.674 |
 Female | 2 | 4 | 4 |  | 4 | 11 | 10 |  |
Age, years | ||||||||
 Range | 39–75 | 43–75 | 38–75 | 0.514 | 47–68 | 53-72 | 34-62 | 0.694 |
 Average | 56.8 | 59.0 | 59.8 |  | 55.4 | 61.2 | 49.8 |  |
Localization of tumor | ||||||||
 Tip | 9 | 8 | 1 | 0.094 | 3 | 6 | 8 | 0.059 |
 Body | 9 | 10 | 12 |  | 7 | 6 | 6 |  |
 Root | 5 | 10 | 8 |  | 3 | 8 | 8 |  |
Pain | ||||||||
 Yes | 18 | 20 | 20 | 0.691 | 10 | 13 | 13 | 0.725 |
 No | 5 | 8 | 1 |  | 3 | 7 | 9 |  |
Margin | ||||||||
 Well-circumscribed | 8 | 8 | 3 | 0.094 | 3 | 8 | 18 | 0.053 |
 Ill-defined | 15 | 20 | 18 |  | 10 | 12 | 4 |  |
Cystic degeneration | ||||||||
 Yes | 14 | 13 | 14 | 0.330 | 7 | 12 | 5 | 0.191 |
 No | 9 | 15 | 7 |  | 6 | 8 | 17 |  |
Sublingual gland duct dilatation | Â | |||||||
 Yes | 10 | 12 | 6 | 0.514 | 3 | 7 | 2 | 0.483 |
 No | 13 | 16 | 15 |  | 10 | 13 | 20 |  |
Lymphatic metastasis | ||||||||
 Yes | 12 | 6 | 4 | 0.021 | 10 | 5 | 3 | 0.000 |
 No | 11 | 22 | 17 |  | 3 | 15 | 19 |  |
HPV | Â | |||||||
 Positive | 14 | 22 | 15 | 0.383 | 9 | 11 | 15 | 0.601 |
 Negative | 9 | 6 | 6 |  | 4 | 9 | 7 |  |