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Fig. 7 | BMC Oral Health

Fig. 7

From: FERMT1 knockdown inhibits oral squamous cell carcinoma cell epithelial-mesenchymal transition by inactivating the PI3K/AKT signaling pathway

Fig. 7

EMT was promoted after IGF-1 treatment at 24 h in si-FERMT1-transfected Tca8113 and SCC15 cells. OSCC cells were treated with 5 ng/ml recombinant human TGF-β1 protein. (A, B) The mRNA expression (A) and protein levels (B) of mesenchymal biomarkers including vimentin, N-cadherin, and MMP-9 and epithelial biomarkers including E-cadherin were measured by qRT-PCR and western blotting. (C) The representative image of western blot. ***P < 0.001, si-FERMT1 + IGF-1 vs si-FERMT1 + PBS

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BMC Oral Health

ISSN: 1472-6831

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