Fig. 5From: Effect of glucose mediated oxidative stress on apoptotic gene expression in gingival mesenchymal stem cellsA This graph shows pro-apoptotic genes of BCL2 Family. The genes BCL2L14, PMAIP1 and BCL2L11 showed significant fold change. B Anti-apoptotic genes of BCL-2 family were also down-regulated, especially BCL2 gene. C It shows down regulated pro-apoptotic genes of BCL-2 family that mainly play role in mitochondrial apoptosis. D This figure includes initiator caspases in which only Casp 8 was increased because it is primarily involved in extrinsic pathway of apoptosis. E The executioner caspases displayed lower expression, except CASP8AP2 gene. F All inflammatory caspases show reduced expression. However, the difference among most genes was not found to be statistically significant. (*P value ≤ 0.05)Back to article page