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Table 4 Association between TAS2R38 genotypes and periodontal disease

From: TAS2R38 polymorphisms and oral diseases in Thais: a cross-sectional study

Prevalence

TAS2R38 Genotype (N = 238)

p for trendb

PAV/PAV (n = 109)

PAV/AVI (n = 101)

AVI/AVI (n = 28)

%

OR [95%CI]a

%

OR [95%CI]

%

OR [95%CI]

PD

 ≥ 4 mm

86.2

Reference

70.3

0.4 [0.2–0.8]

82.1

0.7 [0.2–2.2]

0.10

 ≥ 5 mm

35.8

Reference

25.7

0.6 [0.3–1.1]

14.3

0.3 [0.1–0.9]

0.02*

CAL

 ≥ 3 mm

89.9

Reference

80.2

0.5 [0.2–1.0]

82.1

0.5 [0.2–1.6]

0.10

 ≥ 4 mm

38.5

Reference

36.6

0.9 [0.3–1.6]

25.0

0.5 [0.2–1.4]

0.26

 ≥ 5 mm

19.3

Reference

13.9

0.7 [0.3–1.4]

7.1

0.3 [0.1–1.5]

0.09

Extent (% sites)

Mean ± SD

Mean ± SD

Mean ± SD

p valueb

PD

 ≥ 4 mm

4.7 ± 6.5

3.8 ± 5.6

3.2 ± 3.7

0.14

 ≥ 5 mm

0.7 ± 2.1

0.6 ± 1.7

0.3 ± 1.0

0.09

CAL

 ≥ 3 mm

9.4 ± 16.5

8.1 ± 12.6

6.7 ± 11.5

0.81

 ≥ 4 mm

3.1 ± 9.5

2.2 ± 6.9

1.5 ± 5.0

0.42

 ≥ 5 mm

1.2 ± 4.4

0.8 ± 3.3

0.6 ± 2.6

0.27

  1. PD probing depth, CAL clinical attachment loss, SD standard deviation
  2. *Statistically significant trend
  3. aLogistic regression
  4. bKruskal–Wallis test