Cytotoxic effects of different detergent containing children's toothpastes on human gingival epithelial cells

Birant, Sinem; Duran, Yazgul; Akkoc, Tunc; Seymen, Figen

doi:10.1186/s12903-022-02089-2

BMC Oral Health

Table 4 Univariate tests and pairwise comparisons of viable, early apoptotic, late apoptotic and necrotic cell rates of gingival epithelial cells between concentration groups in each toothpaste groups

From: Cytotoxic effects of different detergent containing children's toothpastes on human gingival epithelial cells

Variable	Brands	Concentration				p
Variable	Brands	0.40%	20%	50%	80%	p
Viable	Colgate 6+	75.74 ± 3.18A	47.56 ± 3.49B	30.77 ± 4.26C	13.04 ± 2.98D	0.000*
	Splat Juicy	90.14 ± 0.95A	85.1 ± 1.77B	84.82 ± 1.6B	83.19 ± 1.88B	0.000*
	Sensodyne Pronamel 6+	84.66 ± 1.58A	78.8 ± 1.16B	67.47 ± 1.68C	57.63 ± 0.83D	0.000*
	Nenedent Kids	80.23 ± 0.93A	64.21 ± 0.91B	55.17 ± 1.2C	39.15 ± 0.91D	0.000*
	Perlodent Junior 6+	78.66 ± 1.84A	64.75 ± 0.91B	45.21 ± 1.81C	30.43 ± 4.05D	0.000*
Early apoptotic	Colgate 6+	3.38 ± 2.01A	9.75 ± 3.55B	33.83 ± 2.81C	28.11 ± 3.07D	0.000*
	Splat Juicy	3.12 ± 1.48	2.52 ± 1.14	2.29 ± 0.78	1.97 ± 0.4	0.745
	Sensodyne Pronamel 6+	1.85 ± 0.53A	4.52 ± 0.67B	12.09 ± 1.11C	9.73 ± 0.57C	0.000*
	Nenedent Kids	4.24 ± 0.98A	10.55 ± 1.79B	8.69 ± 1.36B	38.08 ± 1.27C	0.000*
	Perlodent Junior 6+	2.83 ± 0.67A	6.39 ± 1.14B	10.9 ± 0.99C	17.82 ± 3.44D	0.000*
Late apoptotic	Colgate 6+	5.73 ± 1.66A	11.23 ± 3.2B	10.29 ± 2.55AB	37.19 ± 2.68C	0.000*
	Splat Juicy	1.93 ± 0.32	3.51 ± 0.65	3.87 ± 0.96	3.46 ± 0.97	0.238
	Sensodyne Pronamel 6+	0.70 ± 0.37A	1.5 ± 0.37A	5.25 ± 0.64B	11.96 ± 1.02C	0.000*
	Nenedent Kids	0.89 ± 0.26A	7.65 ± 1B	12.31 ± 0.53C	7.65 ± 0.6B	0.000*
	Perlodent Junior 6+	6.13 ± 1.01A	3.66 ± 0.64A	10.9 ± 1.19B	18.78 ± 4.84C	0.000*
Necrotic	Colgate 6+	15.16 ± 2.4A	31.46 ± 4B	25.11 ± 2.91C	21.67 ± 2.84C	0.000*
	Splat Juicy	4.79 ± 0.54A	8.86 ± 0.87B	9.03 ± 1.03B	11.39 ± 1.53C	0.000*
	Sensodyne Pronamel 6+	12.79 ± 0.96A	15.18 ± 1.09B	15.19 ± 1.28B	20.69 ± 0.91C	0.000*
	Nenedent Kids	14.65 ± 0.61A	17.6 ± 1.1B	23.83 ± 0.7C	15.15 ± 0.92A	0.000*
	Perlodent Junior 6+	12.35 ± 0.68A	25.21 ± 1.3B	31.99 ± 1.2C	32.97 ± 3.99C	0.000*

Each F tests the simple effects of concentration within each level combination of the other effects shown. These tests are based on the linearly independent pairwise comparisons among the estimated marginal means
A-B-C-D: There is no difference between the groups with the same
Univariate Test,; Tukey post-hoc Test
*Significant p value at 0.05 level

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