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Table 1 Top 10 nodes with higher degree in transcription factor–mRNA regulatory network

From: Identification of microRNA–mRNA–TF regulatory networks in periodontitis by bioinformatics analysis

Node name

Degree

Regulation

TF

RASGRP3

5

Up

SPI1, SPIB, SRF, CEBPB, NFATC1

MEF2C

5

Up

SPI1, SPIB, SRF, CEBPB, NFATC1

LCP1

5

Up

SPI1, SPIB, SRF, CEBPB, NFATC1

RGS2

4

Up

SPI1, SPIB, CEBPB, NFATC1

TRIB1

4

Up

SPI1, SPIB, CEBPB, NFATC1

IRF4

4

Up

SPI1, SPIB, CEBPB, NFATC1

LYN

4

Up

SPI1, SRF, CEBPB, NFATC1

DUSP5

4

Up

SPI1, SPIB, SRF, CEBPB

MMP9

4

Up

SPI1, SPIB, SRF, CEBPB

HSD11B1

3

Up

SPIB, SRF, CEBPB