Fig. 2

Inflammatory cytokines mRNA expression patterns in hDPSCs triggered by E. coli or P. gingivalis LPS. A IL-6, B IL-8, C COX-2 D IL-1β, and E TNF-α mRNA. Cells are stimulated by 1 μg/mL LPS from E. coli or P. gingivalis for 0.75,1.5, 3, 6, 12, and 24 h, respectively. The cells without LPS treatment (untreated cells) were used as the control group. This figure is a typical one of three independent experiments with three replications for each experiment. Data are shown as mean ± SD (n = 3). Y-axis represents the relative fold expression of inflammatory mediators relative to the control group. *p < 0.05, vs the control group at the same time point