Table 2 North versus Central-South differences between 270 K-OLP and 270 nK-OLP in systemic diseases and drug consumption
K-OLPs (N:270) | p value | nK-OLPs (N:270) | p value | |||
|---|---|---|---|---|---|---|
Nord (N:135) | Central/South (N:135) | Nord (N:135) | Central/South (N:135) | |||
N/Frequency (%) | N/Frequency (%) | |||||
Systemic diseases | ||||||
Essential hypertension | 40 (29.6) | 50 (37.9) | 0.132 | 61 (45.2) | 67 (49.6) | 0.542 |
Hypercholesterolemia | 26 (19.3) | 32 (23.7) | 0.245 | 28 (20.07) | 35 (25.9) | 0.388 |
Previous myocardial infarction | 2 (1.5) | 2 (1.5) | 0.459 | 3 (2.2) | 2 (1.5) | 1 |
Diabetes mellitus type 2 | 9 (6.6) | 14 (10.3) | 0.458 | 11 (8.1) | 15 (11.1) | 0.825 |
Asthma | 2 (1.5) | 3 (2.2) | 1 | 5 (3.7) | 9 (6.7) | 0.411 |
Gastro-esophageal reflux disease | 17 (12.6) | 22 (16.3) | 0.489 | 36 (26.7) | 21 (15.6) | 0.036* |
Hepatitis B | 3 (2.2) | 0 (0) | 0.247 | 0 (0) | 1 (0.7) | 1 |
Hepatitis C | 3 (2.2) | 3 (2.2) | 1 | 4 (3.0) | 3 (2.2) | 1 |
Endocrine disease | 4 (3.0) | 7 (5.2) | 0.54 | 5 (3.7) | 6 (4.4) | 0.411 |
Hypothyroidism | 17 (12.6) | 17 (12.6) | 1 | 19 (14.1) | 11 (8.1) | 0.174 |
Hyperthyroidism | 2 (1.5) | 3 (2.2) | 1 | 4 (3.0) | 3 (2.2) | 1 |
Benign prostatic hypertrophy | 7 (5.2) | 9 (6.7) | 0.798 | 7 (5.2) | 8 (5.9) | 1 |
Previous malignant disease | 12 (8.9) | 11 (8.1) | 1 | 12 (8.9) | 11 (8.1) | 1 |
Drug consumption | ||||||
Beta‐Adrenergic receptor blockers | 17 (12.6) | 23 (17.0) | 0.392 | 38 (28.1) | 22 (16.3) | 0.028 |
Angiotensin II receptor blockers | 11 (8.1) | 11 (8.1) | 1 | 12 (8.9) | 9 (6.7) | 0.65 |
Diuretics | 7 (5.2) | 13 (9.6) | 0.245 | 5 (3.7) | 18 (13.3) | 0.008** |
Calcium channel blockers | 6 (4.4) | 8 (5.9) | 0.785 | 14 (10.4) | 10 (7.5) | 0.522 |
ACE-inhibitors | 10 (7.4) | 16 (11.9) | 0.302 | 24 (17.8) | 29 (21.5) | 0.54 |
Simvastatin | 14 (10.4) | 21 (15.6) | 0.277 | 23 (17) | 30 (22.2) | 0.358 |
Metformin | 7 (5.2) | 15 (11.1) | 0.118 | 7 (5.2) | 11 (8.1) | 0.465 |
Insulin | 3 (2.2) | 5 (3.7) | 0.772 | 3 (2.2) | 4 (3.0) | 1 |
Antiplatelets | 17 (12.6) | 9 (6.7) | 0.148 | 17 (12.6) | 20 (14.8) | 0.724 |
Blood thinners | 4 (3.0) | 10 (7.4) | 0.168 | 1 (0.7) | 11 (8.1) | 0.005** |
Levothyroxine sodium | 16 (11.9) | 20 (14.8) | 0.592 | 19 (14.1) | 13 (9.6) | 0.347 |
Proton pump inhibitors | 14 (10.4) | 20 (14.8) | 0.359 | 26 (19.3) | 29 (21.5) | 0.763 |