Changes in salivary matrix metalloproteinase-3, -8, and -9 concentrations after 6 weeks of non-surgical periodontal therapy

Table 2 Differences in clinical parameters

Parameter	Periodontal status	Baseline	Week 3	Baseline to week 3		Week 6	Baseline to week 6
Parameter	Periodontal status	Baseline	Week 3	Difference	p-value*	Week 6	Difference	p-value*
PD (mm)	Periodontitis	4.07 ± 2.35	3.67 ± 1.68	0.4 ± 1.78	< 0.001	3.13 ± 1.66	0.94 ± 1.16	0.064
	Health participants	3.16 ± 1.98	3.02 ± 1.49	0.14 ± 1.33	0.044	2.98 ± 1.78	0.18 ± 0.98	0.079
	p-value^†	< 0.001	< 0.001			< 0.001
CAL (mm)	Periodontitis	4.89 ± 2.88	4.32 ± 1.90	0.57 ± 1.15	0.048	3.99 ± 2.78	0.99 ± 1.58	0.040
	Health participants	3.71 ± 2.56	2.92 ± 1.32	0.79 ± 1.42	0.088	2.90 ± 1.78	0.81 ± 1.82	< 0.001
	p-value^†	< 0.001	< 0.001			< 0.001
Gingival bleeding (%)	Periodontitis	67.01 ± 78.32	34.67 ± 55.51	32.34 ± 52.39	< 0.001	23.54 ± 45.66	43.47 ± 62.39	< 0.001
	Health participants	29.95 ± 51.23	25.45 ± 30.07	4.5 ± 16.98	< 0.001	20.90 ± 52.65	9.05 ± 17.66	< 0.001
	p-value^†	< 0.001	< 0.001			< 0.001

ISSN: 1472-6831