Evaluation of cinnamaldehyde mucoadhesive patches on minor recurrent aphthous stomatitis: a randomized, double-blind, placebo-controlled clinical trial

Table 2 Mean ± SD of ulcer size and pain intensity during the study days in the two groups

Variable	Days	Group		P-value	P-value
Variable	Days	Cinnamaldehyde	Placebo	P-value	P-value
Ulcer size (millimeters)	0	4.4 ± 1.5	4.5 ± 1.47	0.666	< 0.001*
	3	2.27 ± 1.35	4.8 ± 1.33	< 0.001 *
	5	0.59 ± 0.95	2.81 ± 1.65	< 0.001 *
	7	0.04 ± 0.21	1.5 ± 1.26	< 0.001 *
	P-value	< 0.001 *	< 0.001 *
Pain intensity (after meals)	0	6.77 ± 2.18	8.0 ± 1.34	0.07	< 0.001*
	1	5.5 ± 2.62	7.17 ± 1.35	0.024 *
	2	3.79 ± 2/32	7.02 ± 1.71	< 0.001 *
	3	2.08 ± 1.86	6.1 ± 1.8	< 0.001 *
	4	0.98 ± 1.28	4.98 ± 2.18	< 0.001 *
	5	0.32 ± 0.74	3.97 ± 2	< 0.001 *
	6	0.0 ± 0.0	2.43 ± 1.72	< 0.001 *
	7	0.0 ± 0.0	1.21 ± 1.28	< 0.001 *
	P-value	< 0.001 *	< 0.001 *

ISSN: 1472-6831