Group | 1st hour | 1st day | 7th day | 14th day | 21st day | **p-value |
---|---|---|---|---|---|---|
1 | 5.931 ± 0.686a (0.0116) | 14.792 ± 1.229b (0.0289) | 12.321 ± 1.641b (0.0240) | 3.155 ± 0.546c (0.0062) | 2.567 ± 0.322c (0.0050) | < 0.001 |
2 | 7.881 ± 1.790ac (0.0154) | 17.206 ± 2.774b (0.0336) | 12.969 ± 1.975a (0.0247) | 4.242 ± 0.679c (0.0083) | 3.284 ± 0.399d (0.0064) | < 0.001 |
3 | 8.465 ± 1.614ab (0.0165) | 15.876 ± 2.456a (0.0310) | 12.642 ± 2.683b (0.0247) | 3.750 ± 1.979c (0.0073) | 3.064 ± 0.554c (0.0060) | < 0.001 |
4 | 4.237 ± 0.494a (0.0083) | 10.658 ± 1.023b (0.0208) | 8.587 ± 0.638c (0.0168) | 2.315 ± 0.188d (0.0045) | 2.163 ± 0.292d (0.0042) | < 0.001 |
5 | 33.278 ± 10.622ab (0.0649) | 35.731 ± 7.434a (0.0697) | 20.557 ± 3.208b (0.0401) | 4.954 ± 0.519c (0.0097) | 3.021 ± 0.281d (0.0059) | < 0.001 |
6 | 4.738 ± 1.335a (0.0092) | 10.750 ± 1.392b (0.0210) | 8.922 ± 1.218c (0.0174) | 2.526 ± 0.577d (0.0049) | 2.197 ± 0.411e (0.0043) | < 0.001 |
7 | 2.784 ± 0.663a (0.0054) | 7.683 ± 0.907b (0.0150) | 5.999 ± 0.648c (0.0117) | 1.543 ± 0.257d (0.0030) | 1.413 ± 0.239d (0.0028) | < 0.001 |
8 | 2.969 ± 0.306a (0.0058) | 8.586 ± 0.614b (0.0168) | 6.736 ± 0.666c (0.0131) | 1.592 ± 0.197d (0.0031) | 1.381 ± 0.142e (0.0027) | < 0.001 |
9 | 3.310 ± 0.856a (0.0065) | 8.084 ± 1.840b (0.0158) | 6.587 ± 1.411b (0.0129) | 1.700 ± 0.292a (0.0033) | 1.472 ± 0.207c (0.0029) | < 0.001 |
10 | 0.190 ± 0.035a (0.0004) | 0.745 ± 0.100b (0.0015) | 1.217 ± 0.105c (0.0024) | 0.315 ± 0.042d (0.0006) | 0.144 ± 0.025a (0.0003) | < 0.001 |
11 | 5.287 ± 1.167a (0.0103) | 12.460 ± 0.996b (0.0243) | 10.587 ± 1.214b (0.0207) | 2.920 ± 0.252a (0.0057) | 2.450 ± 0.147c (0.0048) | < 0.001 |
12 | 2.381 ± 0.781ab (0.0046) | 3.137 ± 1.167a (0.0061) | 2.894 ± 1.056a (0.0056) | 1.123 ± 0.368b (0.0022) | 0.801 ± 0.362c (0.0016) | < 0.001 |
*p-value | < 0.001 | < 0.001 | < 0.001 | < 0.001 | < 0.001 |