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Table 3 Univariate and multivariate analyses of prognostic factors in 365 patients with OSCC

From: Prognostic role of an inflammation scoring system in radical resection of oral squamous cell carcinoma

Variable

Univariate survival analysis

Multivariate survival analysis

Hazard ratio

95% CI

P-value

Hazard ratio

95% CI

P-value

Sex

1.054

0.662–1.679

0.823

   

Currently smoking

0.931

0.426–2.031

0.857

   

Currently drinking

0.869

0.350–2.157

0.761

   

Age

1.858

1.036–3.333

0.038

1.930

1.051–3.546

0.034

Tumor size

3.355

2.024–5.555

 < 0.001

2.469

1.408–4.329

0.002

Cervical nodal metastasis

 N0

Ref

  

Ref

  

 N1

4.807

2.739–8.403

 < 0.0001

2.688

1.373–5.263

0.004

 N2

2.941

1.344–6.410

0.007

3.663

0.686–3.787

0.273

Cancer subsites

 Lip

Ref

     

 Gingval

0.788

0.267–2.320

0.665

   

 Buccal

1.194

0.646–2.206

0.572

   

 Mouth floor

1.252

0.686–2.287

0.464

   

 Tongue

0.765

0.178–3.286

0.719

   

NLR

2.618

1.640–4.180

 < 0.001

1.978

1.194–3.274

0.008

Fibrinogen (mg/dL)

8.128

3.641–18.144

 < 0.001

5.301

2.426–11.581

 < 0.001

MPV

2.707

1.577–4.645

 < 0.001

1.804

1.041–3.127

0.035

PLR

 < 150

Ref

  

Ref

  

 ≥ 150 ≤ 300

6.774

2.913–15.750

 < 0.001

2.468

1.053–5.783

0.037

 > 300

6.758

3.406–13.406

 < 0.001

2.388

1.152–4.951

0.019

F-NLR

 0

Ref

  

Ref

  

 1

19.989

6.847–58.359

 < 0.001

26.566

5.589–126.258

 < 0.001

 2

2.621

1.612–4.261

 < 0.001

3.895

1.321–11.485

0.014

LVI

2.290

1.401–3.744

0.001

2.079

1.234–3.496

0.006

PNI

2.390

0.750–7.616

0.141

   
  1. Statistically significant values are shown in bold
  2. F-NLR the combined fibrinogen and NLR score, NLR Neutrophil-to-lymphocyte ratio, MPV mean platelet volume, PNI perineural invasion, LVI lymphatic and vascular invasion, OSCC oral squamous cell carcinoma
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BMC Oral Health

ISSN: 1472-6831

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