Fig. 2

The expression of circRNAs in DPSCs and their circular structure validation. A The circRNA-miRNA-mRNA linkage was plotted using Cytoscape; red represented circRNA, green represented miRNA, and blue indicated mRNA. B The expression changes of these 11 circRNAs in RNA sequencing data were shown in the column chart. N = 3, T-test; **, indicates P value less than 0.01; ***, indicates P value less than 0.001. C The circular structure was verified using agarose gel electrophoresis and Sanger sequencing. The original blots were included in a Additional file 1, in which the edges with no signals were not included. D The expression of circRNAs was identified using the qRT-PCR protocol in TNF-α treated DPSCs and NC DPSCs. N = 3, T-test; ns, indicates no difference; *, indicates P value less than 0.05; **, indicates P value less than 0.01; ***, indicates P value less than 0.001; ****, indicates P value less than 0.0001