Fig. 7From: Effect of Enterococcus faecalis OG1RF on human calvarial osteoblast apoptosisA proposed model of the mechanism of E. faecalis-induced-apoptosis in osteoblasts. E. faecalis OG1RF induced apoptosis in human primary osteoblasts, and both the extrinsic and intrinsic caspases were activated. Anti-apoptotic BCL-2 and BCL2A1, and pro-apoptotic BCL2L11, HRK, BIK, BMF, NOXA, and Beclin-1 were also involved in osteoblast apoptosis induced by E. faecalisBack to article page