Fig. 5
From: Role of PI3K in the bone resorption of apical periodontitis
Detection of related genes and proteins after treatment of osteoclasts and osteoblasts with LPS. A mRNA expression of PI3K (P = 0.038), Acp5 (P < 0.001) and NFATc1 (P = 0.002) in osteoblasts under the action of LPS; B mRNA expression of PI3K (P < 0.001), BMP-2 (P = 0.002) and Runx2 (P = 0.039) in osteoblasts under the action of LPS. C Expression of PI3K, TRAP and NFATc1 proteins in osteoclasts under the action of LPS; D statistical analysis of PI3K (P = 0.032), TRAP (P = 0.022) and NFATc1 (P = 0.028) protein expression in osteoclasts; E expression of PI3K, BMP-2 and Runx2proteins in osteoblasts under the action of LPS; F statistical analysis of PI3K (P = 0.045), Runx2 (P = 0.018) and BMP-2 (P = 0.021) protein expression in osteoblasts.*P < 0.05, representing a significant difference between the different groups