Table 1 Patient characteristics and salivary autoantibody levels

No. of cases (%)

337

190 (56.4)

147 (43.6)

–

Sex, male, n (%)

331 (98.2)

188 (98.9)

143 (97.3)

0.41^a

Age, range

31–82

32–82

31–78

0.003^b

  Years, median (IQR)

50.4 (17)

51.8 (15)

49.2 (19)

Smoking, n (%)

306 (90.8)

176 (92.6)

130 (88.4)

0.258^c

Alcohol consumption, n (%)

118 (35.0)

81 (42.6)

37 (25.2)

0.001^c

Betel nut chewing, n (%)

271 (80.4)

175 (92.1)

96 (65.3)

< 0.001^c

Autoantibodies, MFI, median (IQR)

  Anti-ANXA2

2727.2 (2611.4)

2791.8 (3079.5)

2600.1 (2244.6)

0.253^b

  Anti-CA2

1191.2 (1232.8)

1446.0 (1509.2)

1020.0 (947.3)

< 0.001^b

  Anti-HSPA5

607.8 (722.8)

757.5 (892.1)

457.1 (484.0)

 < 0.001^b

  Anti-ISG15

1273.7 (1299.0)

1506.0 (1635.8)

1021.4 (1004.4)

< 0.001^b

  Anti-KNG1

4176.5 (4720.2)

4814.0 (6782.6)

3379.6 (2981.0)

< 0.001^b

  Anti-MMP1

1426.3 (1214.5)

1647.8 (1523.4)

1239.3 (953.8)

< 0.001^b

  Anti-MMP3

3907.2 (548.4)

4018.6 (777.1)

3828.9 (405.2)

< 0.001^b

  Anti-p53

1616.7 (1782.1)

1814.1 (2432.3)

1485.1 (1437.4)

0.003^b

  Anti-PRDX2

1038.0 (1286.3)

1336.4 (1525.1)

813.0 (865.5)

< 0.001^b

  Anti-SPARC

707.0 (724.8)

833.9 (956.5)

555.2 (507.2)

< 0.001^b