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Fig. 6 | BMC Oral Health

Fig. 6

From: Comprehensive analysis of M2 macrophage-derived exosomes facilitating osteogenic differentiation of human periodontal ligament stem cells

Fig. 6

Identification of DE-miRNAs in M0-exo and M2-exo. A Differential expression analysis of miRNAs in M0-exo and M2-exo. From left to right are heat map, scatterplot and volcanoplot. Threshold: absolute log2 FC ≥ 1 and P < 0.05. RT-qPCR was applied to examine the expression of (B) TOP5 down-regulated DE-miRNA and C TOP5 up-regulated DE-miRNA in M0-exo and M2-exo. C Prediction of target genes for (left) All DE-miRNA, (middle) down DE-miRNA and (right) up DE-miRNA using miRWalk and miRNADB databases. Values are mean ± SD (n = 3 for each group). Compared to M0-exo group, **P < 0.01, ***P < 0.001

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BMC Oral Health

ISSN: 1472-6831

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