Table 1 Intra-mouthrinse comparisons of viability of salivary microbiota (%), measured as fluorescence, after treatment with placebo (sterile water), CPC, O-cymen-5-ol, and CPC + O-cymen-5-ol
Time | Mouthrinse | Mean ± SD | 95% Conf. Interval | p-value |
|---|---|---|---|---|
15 min | Placebo | 92.6 ± 18.7 | 80.03–105.12 | 0.38 |
CPC | 48.0 ± 13.9 | 40.98–56.99 | < 0.001 | |
O-Cymen-5-ol | 79.8 ± 21.0 | 67.71–91.90 | < 0.05 | |
CPC + O-Cymen-5-ol | 49.4 ± 14.1 | 40.98–56.99 | < 0.001 | |
30 min | Placebo | 96.0 ± 15.6 | 85.52–106.52 | 0.64 |
CPC | 58.3 ± 12.9 | 50.80–65.71 | < 0.001 | |
O-Cymen-5-ol | 82.7 ± 23.0 | 69.46–95.98 | < 0.05 | |
CPC + O-Cymen-5-ol | 54.8 ± 22.9 | 41.60–68.02 | < 0.001 | |
1 h | Placebo | 97.7 ± 23.6 | 81.85–113.59 | 0.80 |
CPC | 64.9 ± 13.6 | 57.04–72.75 | < 0.001 | |
O-Cymen-5-ol | 85.1 ± 21.9 | 72.45–97.76 | 0.05 | |
CPC + O-Cymen-5-ol | 63.6 ± 21.1 | 51.42–75.82 | < 0.001 | |
2 h | Placebo | 99.6 ± 19.3 | 86.65–112.62 | 0.98 |
CPC | 69.8 ± 17.0 | 60.03–79.67 | < 0.001 | |
O-Cymen-5-ol | 88.0 ± 28.7 | 71.44–104.55 | 0.12 | |
CPC + O-Cymen-5-ol | 67.5 ± 16.4 | 58.03–76.94 | < 0.001 | |
3 h | Placebo | 98.8 ± 19.1 | 86.00–111.69 | 0.91 |
CPC | 78.0 ± 14.0 | 69.92–86.09 | < 0.05 | |
O-Cymen-5-ol | 90.4 ± 27.5 | 74.53–106.23 | 0.22 | |
CPC + O-Cymen-5-ol | 67.8 ± 25.7 | 52.94–82.65 | < 0.001 | |
4 h | Placebo | 99.8 ± 17.5 | 87.97–111.52 | 0.93 |
CPC | 91.0 ± 25.5 | 76.28–105.74 | 0.25 | |
O-Cymen-5-ol | 92.4 ± 26.7 | 76.91–107.81 | 0.34 | |
CPC + O-Cymen-5-ol | 80.3 ± 22.8 | 67.15–93.50 | < 0.05 |