Table 2 Intra-mouthrinse comparisons of viability of salivary microbiota (%), measured under CLSM, after treatment with placebo (sterile water), CPC, O-cymen-5-ol, and CPC + O-cymen-5-ol.
Time (in min) | Mouthrinse | Mean ± SD | 95% Conf. Interval | p-value |
|---|---|---|---|---|
15 min | Placebo | 86.3 ± 10.7 | 79.14–93.48 | 0.09 |
CPC | 54.8 ± 23.0 | 41.50–68.06 | < 0.001 | |
O-Cymen-5-ol | 76.3 ± 17.1 | 66.36–86.14 | < 0.001 | |
CPC + O-Cymen-5-ol | 47.4 ± 11.9 | 40.49–54.30 | < 0.001 | |
30 min | Placebo | 95.3 ± 16.0 | 84.53–106.01 | 0.86 |
CPC | 67.4 ± 22.7 | 54.25–80.44 | < 0.001 | |
O-Cymen-5-ol | 84.4 ± 12.9 | 76.97–91.89 | < 0.05 | |
CPC + O-Cymen-5-ol | 56.2 ± 12.7 | 48.88–63.49 | < 0.001 | |
1 h | Placebo | 92.1 ± 5.9 | 88.15–96.09 | 0.48 |
CPC | 68.0 ± 17.0 | 58.20–77.83 | < 0.001 | |
O-Cymen-5-ol | 82.0 ± 12.4 | 74.80–89.10 | < 0.05 | |
CPC + O-Cymen-5-ol | 58.7 ± 8.9 | 53.54–63.87 | < 0.001 | |
2 h | Placebo | 93.0 ± 11.1 | 85.54–100.52 | 0.58 |
CPC | 68.9 ± 19.5 | 57.65–80.14 | < 0.001 | |
O-Cymen-5-ol | 88.2 ± 8.0 | 83.57–92.80 | 0.14 | |
CPC + O-Cymen-5-ol | 60.5 ± 18.0 | 50.11–70.86 | < 0.001 | |
3 h | Placebo | 95.3 ± 8.0 | 89.94–100.69 | 0.87 |
CPC | 79.3 ± 18.5 | 68.63–90.06 | < 0.001 | |
O-Cymen-5-ol | 92.0 ± 9.9 | 86.34–97.73 | 0.44 | |
CPC + O-Cymen-5-ol | 67.2 ± 11.8 | 60.44–74.05 | < 0.001 | |
4 h | Placebo | 96.2 ± 8.3 | 90.63–101.84 | 0.88 |
CPC | 93.1 ± 22.8 | 79.95–106.29 | 0.57 | |
O-Cymen-5-ol | 94.1 ± 9.1 | 88.84–99.40 | 0.70 | |
CPC + O-Cymen-5-ol | 81.4 ± 13.8 | 73.45–89.43 | < 0.05 |