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Table 4 Monomer release from resin based materials in different immersion time periods

From: Effect of topical fluoride applications on residual monomer release from resin-based restorative materials

Monomer

Material

Fluoride application

Immersion time-periods

p*

10 min

1 h

24 h

30d

TEGDMA

FBF

Control

0.384 (0.07–0.87)

1.083 (0.59–1.333)

0.908 (0.28–0.29)

0.978 (0.24–1.33)

0.392

APF

1.397 (0.16–2.10)

0.699 (0.31–0.38)

0.210 (0.04–1.15)

0.699 (0.24–1.50)

0.050

NaF

0.035 (0.00–1.47)

0.599 (0.21–1.36)

0.733 (0.42–1.68)

0.524 (0.38–0.87)

0.145

p

0.049

0.443

0.305

0.555

 

DXP

Control

2.305 (0.00–3.95)

4.121 (1.75–5.03)1

5.064 (0.00–8.66)

3.982 (2.20–5.06)

0.095

APF

2.375 (1.26–7.09)

1.432 (1.01–2.34)2

4.331 (2.62–6.95)

1.991(1.68–4.16)

0.251

NaF

1.013 (0.59–1.61)b

1.257 (0.87–1.47)2.b

3.143 (2.17–3.77)a

1.816 (1.08–2.59)b

0.004

p

0.168

0.001

0.559

0.025

 

Z550

Control

0.384 (0.00–1.29)

0.105 (0.00–0.45)2

0.419 (0.24–0.59)2

0.768 (0.59–0.91)1

0.041

APF

0.105 (0.00–0.73)

0.105 (0.00–0.42)2

0.699 (0.42–1.01)2

0.349 (0.24–0.56)2

0.054

NaF

1.362 (0.91–11.60)

0.768 (0.38–1.05)1

1.432 (0.73–1.82)1

0.664 (0.38–1.22)1

0.095

p

0.051

0.001

0.003

0.016

 

HEMA

FBF

Control

49.447 (9.22–223.22)

71.769 (22.67–171.74)

38.612 (24.97–160.60)

42.108 (0.00–71.85)

0.178

APF

29.968 (2.04–77.49)

13.447 (11.14–50.72)

21.938 (17.29–53.02)

16.828 (9.99–33.04)

0.106

NaF

33.003 (12.29–134.09)

35.808 (14.60–90.29)

53.980 (22.28–113.34)

17.865 (8.07–93.36)

0.178

p

0.285

0.151

0.222

0.616

 

DXP

Control

6.378 (4.61–9.22)1

11.872 (8.84–13.06)

16.751 (8.84–21.90)

19.978 (12.68–22.28)

0.062

APF

12.256 (7.68–18.83)2.b

17.712 (7.30–27.66)b

27.317 (17.67–33.81)a

18.403 (10.37–24.21)b

0.003

NaF

13.524 (10.76–18.44)2

22.284 (18.06–28.82)

22.245 (8.45–36.88)

3.458 (1.77–4.19)

0.178

p

0.012

0.024

0.149

0.602

 

Z550

Control

0.231 (0.19–3.99)2

0.576 (0.50–1.38)

0.307 (0.00–0.35)2

0.192 (0.00–1.04)

0.145

APF

12.026 (0.58–2.08)2

0.615 (0.00–1.99)

1.037 (0.58–1.35)2

0.845 (0.00–1.38)

0.145

NaF

26.010 (12.03–38.38)1.a

4.149 (1.69–19.36)b

4.034 (2.61–6.76)1.b

0.922 (0.65–1.42)b

0.004

p

0.0001

0.050

0.0001

0.077

 

UDMA

FBF

Control

41.697 (21.49–143.60)a

18.083 (9.15–99.77)b

17.232 (10.64–68.72)b

8.297 (5.32–27.87)b

0.003

APF

19.572 (16.81–52.33)a

9.786 (7.02–19.57)b

11.275 (9.15–24.89)b

6.595 (4.04–12.34)b

0.003

NaF

36.591 (19.99–83.82)a

23.189 (10.64–49.57)b

26.380 (12.13–50.21)b

7.446 (1.92–12.13)b

0.002

p

0.222

0.224

0.290

0.213

 

DXP

Control

0.000 (0.00–0.00)

0.000 (0.00–0.00)

0.000 (0.00–0.00)

0.000 (0.00–0.00)

APF

0.000 (0.00–0.00)

0.000 (0.00–0.00)

0.000 (0.00–0.00)

0.000 (0.00–0.00)

NaF

0.000 (0.00–0.00)

0.000 (0.00–0.00)

0.000 (0.00–0.00)

0.000 (0.00–0.00)

p

     

Z550

Control

28.507 (22.76–36.17)a

15.743 (14.47–19.99)2.b

16.168 (12.34–17.02)2.b

6.595 (5.53–7.66)2.c

0.002

APF

34.889 (20.85–45.31)a

12.275 (8.51–16.93)2.b

17.445 (15.32–24.68)2.b

7.446 (6.17–11.49)2.c

0.004

NaF

36.804 (19.36–115.52)b

55.950 (16.81–95.52)1.a

54.036 (15.96–72.33)1.a

13.828 (8.72–15.32)1.c

0.019

p

0.171

0.015

0.006

0.0001

 

Bis-GMA

FBF

Control

18.923 (10.93–60.09)a

10.535 (6.63–44.67)b

9.559 (6.63–37.46)b

5.072 (3.71–15.99)b

0.003

APF

11.315 (6.83–23.41)a

4.292 (3.71–8.78)b

5.853 (5.07–12.88)b

3.902 (2.93–7.41)b

0.004

NaF

22.435 (8.97–35.90)a

11.315 (5.27–25.17)b

15.412 (7.22–27.51)b

4.682 (0.59–9.56)b

0.002

p

0.218

0.153

0.233

0.215

 

DXP

Control

0.956 (0.74–1.42)b

1.483 (1.01–11.02)a

2.165 (1.62–3.41)a

2.282 (1.56–3.43)a

0.029

APF

2.146 (1.37–4.68)a

1.385 (1.09–4.45)a

2.712 (1.84–6.30)a

1.092 (0.00–3.00)b

0.018

NaF

1.151 (0.98–3.51)

1.366 (1.01–1.46)

3.180 (1.95–3.84)

1.756 (0.90–2.13)

0.062

p

0.106

0.496

0.423

0.136

 

Z550

Control

18.338 (13.07–23.02)a

7.998 (7.61–10.14)2.b

7.998 (7.02–8.97)2.b

3.512 (2.93–3.71)2.c

0.002

APF

23.800 (13.46–29.46)a

7.355 (5.66–8.97)2.b

8.974 (7.99–13.46)2.b

3.902 (3.36–6.44)2.c

0.004

NaF

31.902 (17.17–65.55)a

31.409 (11.32–51.11)1.a

31.018 (10.34–41.55)1.a

7.803 (5.07–9.36)1.b

0.011

p

0.057

0.009

0.004

0.001

 
  1. p values are based on Kruskal–Wallis test and Bonferroni correction p < 0.05/3 = 0.017 (bolditalics) is significant; *p values based on Friedman Test *p < 0.05 (bold) is significant
  2. Lower letters indicate the difference between lines and numbers indicate the difference between columns
  3. FBF Filtek Bulk Fill Composite, DXP Dyract XP Compomer, Z550 3M ESPE Z550 Nanohybrid Universal Composite, APF Acidulated Phosphate Fluoride Gel, NaF Sodium Fluoride Neutral Gel