Fig. 4
From: Network analysis reveals miRNA crosstalk between periodontitis and oral squamous cell carcinoma
The minimum network of Co-DEmiRNA-Gene. The optimized and minimal network was used to obtain the five key miRNA nodes with the strongest centrality and the highest degree among the 11 DEmiRNAs, including hsa-mir-497-5p, hsa-mir-224-5p, hsa-mir-210-3p, hsa-mir-29c-3p, and hsa-mir-486-5p. The five most critical related gene nodes were also obtained, which were ZNF460, FBN1, CDK6, BTG2, and CBX6 (blue node: DEmiRNA, green node: gene)