Table 4 Top 10 enriched pathways in the Co-DEmiRNA-TF network
From: Network analysis reveals miRNA crosstalk between periodontitis and oral squamous cell carcinoma
KEGG pathway | Value |
|---|---|
Acute myeloid leukemia | 2.72E−08 |
Pathways in cancer | 5.71E−06 |
Chronic myeloid leukemia | 0.000286 |
Epstein-Barr virus infection | 0.000549 |
Transcriptional misregulation in cancer | 0.000553 |
Adipocytokine signaling pathway | 0.00604 |
Pancreatic cancer | 0.00721 |
Small cell lung cancer | 0.00961 |
Toxoplasmosis | 0.0128 |
Jak-STAT signaling pathway | 0.0145 |
Reactome pathway | |
 Pathways in cancer | 0.000125 |
 Legionellosis | 0.00247 |
 Renal cell carcinoma | 0.00549 |
 Adipocytokine signaling pathway | 0.00604 |
 Apoptosis | 0.0103 |
 TGF-beta signaling pathway | 0.0106 |
 MAPK signaling pathway | 0.0117 |
 Chagas disease (American trypanosomiasis) | 0.0118 |
 Toxoplasmosis | 0.0128 |
 Toll-like receptor signaling pathway | 0.0139 |
GO-BP | |
 Positive regulation of transcription from RNA polymerase II promoter | 1.71e−11 |
 Positive regulation of transcription, DNA-dependent | 1.52e−09 |
 Positive regulation of transcription, DNA-dependent | 1.52e−09 |
 Positive regulation of RNA metabolic process | 2.68e−09 |
 Positive regulation of the nucleobase-containing compound metabolic process | 8.02e−09 |
 Regulation of transcription from RNA polymerase II promoter | 1.69e−08 |
 Positive regulation of cellular metabolic process | 5.23e−08 |
 Transcription from RNA polymerase II promoter | 1e−07 |
 Positive regulation of metabolic process | 1.04e−07 |
 Regulation of multicellular organismal process | 1.14e−06 |
GO-MF | |
 Positive regulation of transcription, DNA-dependent | 1.33e−09 |
 Transcription from RNA polymerase II promoter | 8.8e−08 |
 Sequence-specific DNA binding | 5.2e−07 |
 Transcription factor binding | 1.41e−06 |
 DNA binding | 2.8e−06 |
 Negative regulation of transcription, DNA-dependent | 6.39e−05 |
 Chromatin binding | 0.00237 |
 Protein heterodimerization activity | 0.00316 |
 Double-stranded DNA binding | 0.00649 |
 Protein dimerization activity | 0.00704 |
GO-CC | |
 Transcription factor complex | 4.72e−05 |
 Nucleoplasm | 8.93e−05 |
 Nucleoplasm part | 0.000275 |
 Nuclear lumen | 0.00106 |
 Chromatin | 0.00143 |
 Nuclear part | 0.00388 |
 Organelle lumen | 0.00426 |
 Membrane-enclosed lumen | 0.00472 |
 Chromosomal part | 0.0108 |
 Chromosome | 0.0166 |