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Fig. 4 | BMC Oral Health

Fig. 4

From: Systemic inhibition of 5-lipoxygenase by MK-886 exacerbates apical periodontitis bone loss in a mouse model

Fig. 4

Detection of RANK/RANKL/OPG genes after treatment with MK-886. Relative expression of Tnfrsf11a, Tnfsf11 and Tnfrsf11b genes that encode RANK, RANKL and OPG, after inoculation of LPS into root canals and at 7 and 14 days of treatment with MK-886 (median and interquartile range). *p < 0.05 compared with healthy periodontal ligament; #p < 0.05 compared with inoculation of LPS into root canals; &p < 0.05 comparison between 7 and 14 days of the same treatment

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