Fig. 5From: Systemic inhibition of 5-lipoxygenase by MK-886 exacerbates apical periodontitis bone loss in a mouse modelDetection of genes related to bone metabolism after treatment with MK-886. Relative expression of Acp5, Mmp9, Ctsk and Calcr genes that encode the tartrate-resistant acid phosphatase enzyme (TRAP), matrix-9 metalloproteinase, cathepsin K and the calcitonin receptor, after LPS inoculation into root canals, and at 7 and 14 days after treatment with MK-886 (median and interquartile range). *p < 0.05 compared with healthy periodontal ligament; #p < 0.05 compared with inoculation of LPS into the root canals; &p < 0.05 comparison between 7 and 14 days of the same treatmentBack to article page