Fig. 7
From: Oral microbiome contributes to the failure of orthodontic temporary anchorage devices (TADs)
Differential functions based on the KEGG database. A Enriched KO pathways in failed groups. KO pathways are depicted in rows. The abundance is shown by the color gradient (blue, not detected; red, most abundant). The sample name is displayed in columns. The blue square circle KO pathways are associated with oxidative phosphorylation. The red square circle KO pathways are associated with flagellar assembly and bacterial chemotaxis. B Dynamics of the microbiome associated with successful and failed TADs. On successful TADs, biofilm exists on the head and the neck of the TAD. The surrounding tissue shows minor signs of inflammation. On failed TADs, biofilm also exists on the body of TAD. Peri-implant inflammation and bone resorption occur on the surrounding tissue. Failed TAD demonstrates enriched functions associated with flagellar assembly, bacterial chemotaxis, and oxidative phosphorylation. The pattern was drafted with reference to KEGG imagery[40, 41]