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Fig. 1 | BMC Oral Health

Fig. 1

From: METTL3 enhances dentinogenesis differentiation of dental pulp stem cells via increasing GDF6 and STC1 mRNA stability

Fig. 1

The level of RNA m6A modification increased during dentinogenesis differentiation. A The expression of m6A gradually increased with the dentinogenesis differentiation in mice cervical loop. e Stem cells. f Transit-amplifying cells in labial cervical loop. g Transit-amplifying cells in lingual cervical loop. h)Odontoblasts. B The content of RNA m6A increased in DPSCs during the dentinogenesis differentiation. C Expression levels of RNA m.6A methylation-related genes, METTL3, METTL14, FTO, ALKBH5, were measured by real‐time RT‐PCR on 0, 7 and 14 days after mineralization induction (n = 3). D Western blotting analysis of METTL3 from DPSCs after mineralization induct for 0, 7 and 14 days. β‐ACTIN served as an internal control. *P < 0.05, ***P < 0.001

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BMC Oral Health

ISSN: 1472-6831

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