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Fig. 7 | BMC Oral Health

Fig. 7

From: Low-dose arecoline regulates distinct core signaling pathways in oral submucous fibrosis and oral squamous cell carcinoma

Fig. 7

Representative DMG differential methylation curves in the promoter region between control and low-dose arecoline groups. A Results of visualization mapping based on q-value screening of differential methylation regions in NFs. B Results of visualization mapping based on q-value screening of differential methylation regions in CAL27 cells. q-value < 0.05. The yellow part is the DMR area. The X-axis plots methylation of the 1 kb region extending from the DMR to each side. The top black box indicates the location of the gene promoter and the direction of gene expression in that area. The middle part is the methylation level change curve of the two groups of samples. At the bottom is the CG site density curve. DMG, differentially methylated gene; DMR, differentially methylated region. C1E, CAL27 cells with low-dose arecoline treatment; C1C, CAL27 cells without low-dose arecoline treatment; NF1E, NFs with low-dose arecoline treatment; NF1C, NFs without low-dose arecoline treatment

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BMC Oral Health

ISSN: 1472-6831

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