Fig. 4

Effects of CGF and iRoot BP Plus on cell proliferation and the expression of inflammatory cytokines and dentinogenesis-related genes in LPS-stimulated hDPSCs. A The proliferation of LPS-stimulated hDPSCs at 1, 4, and 7 days. B The expression of dentinogenesis-related genes in inflammatory hDPSCs at 14 days. C The expression of the proinflammatory factors TNF-α, IL-1β, and IL-6 and the anti-inflammatory factors IL-4 and IL-10 at 24 h (+ : P < 0.05, compared with the NC group,*: P < 0.05, compared with the LPS group, **: P < 0.01, compared with the LPS group, #: P < 0.05, compared with CGF-iRoot BP Plus, ##: P < 0.01, compared with CGF-iRoot BP Plus, ###: P < 0.001, compared with CGF-iRoot BP Plus)