Table 3 Outcomes of multivariate analysis

V64 Gy, N (%)

< 27%

≥ 27%

158 (81.9)

35 (18.1)

12 (7.6)

9 (25.7)

0.005

3.67 (2.18–6.43)

Pre-C-CRT tooth extraction, N (%)

< 5

≥ 5

123 (63.7)

70 (36.3)

0 (0.0)

21 (30.0)

< 0.001

11.7 (5.64–18.9)

Post-C-CRT tooth extraction, N (%)

Absent

Present

31 (16.1)

162 (83.9)

0 (0.0)

21 (13.0)

0.005

11.36 (4.72–18.67)

MMD, N (%)

< 50.6 Gy

≥ 50.6 Gy

132 (68.4)

61 (31.6)

9 (6.8)

12 (19.7)

0.012

3.17 (2.56–5.18)

C-CRT to tooth extraction interval, N (%)

> 5.5 mo.

≤ 5.5 mo.

61 (31.6)

132 (68.4)

19 (31.1)

2 (1.6)

< 0.001

7.89 (5.72–16.33)

HPR, N (%)

≤ 0.48

> 0.48

60 (31.1)

133 (68.9)

18 (30.0)

3 (2.3)

< 0.001

9.87 (3.16–20.78)