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Table 5 The median of the XeQoLs before-after treatment difference scores taken from CMC- or trehalose-based oral spray treatment groups

From: Trehalose versus carboxymethylcellulose oral spray for relieving radiation-induced xerostomia in head and neck cancer patients: a randomized controlled trial

Questionnaire

Difference of XeQoL score (Before-After) Median ± IQR

CMC

(n = 35)

Trehalose

(n = 35)

ρ-value

Part 1: Physical

   

Q1: Rate your difficulty in chewing due to dryness

0.00 ± 0.10

0.00 ± 0.00

0.320

Q2: Rate your difficulty in swallowing food due to dryness

0.00 ± 2.00

1.00 ± 2.00

0.381

Q3: Rate your difficulty in talking due to dryness

0.00 ± 1.00

0.00 ± 1.00

0.744

Q4: Rate your taste alteration

0.00 ± 2.00

0.00 ± 1.00

0.628

Part 2: Pain / Discomfort

   

Q5: Rate your feeling dry mouth

2.00 ± 2.00

2.00 ± 2.00

0.841

Q6: Rate the frequency of sipping water (nocturnal)

0.00 ± 0.00

0.00 ± 1.00

0.421

Q7: Rate the frequency of sipping water (daytime)

0.00 ± 2.00

0.00 ± 2.00

0.781

Q8: Rate your pain and discomfort

0.00 ± 0.00

0.00 ± 0.00

0.685

Part 3: Psychological

   

Q9: My mouth/throat dryness interferes with my daily activity

0.00 ± 0.00

0.00 ± 1.00

0.749

Q10: My mouth/throat dryness makes me nervous

0.00 ± 0.00

0.00 ± 1.00

0.753

Q11: My mouth/throat dryness reduces my general happiness

0.00 ± 0.00

0.00 ± 0.00

0.451

Part 4: Social

   

Q12: My mouth/throat dryness makes me uncomfortable speaking in front of other people

0.00 ± 0.00

0.00 ± 0.00

0.655

Q13: My mouth/throat dryness makes me uncomfortable when eating in front of other people

0.00 ± 0.00

0.00 ± 0.00

0.977

Q14: My mouth/throat dryness makes me from socializing (going out)

0.00 ± 0.00

0.00 ± 0.00

0.645

  1. Mann-Whitney U test was used to compare the XeQoLs before-after treatment difference scores between both treatment group