| Baseline | P | 6 months | P | 12 months | P | Δ0-6 | P | Δ6-12 | P | Δ0-12 | P |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean PD | ||||||||||||
 Test | 4.5 ± 0.10 |  | 4.1 ± 0.10 |  | 4.2 ± 0.11 |  | -0.4 ± 0.12 | 0.006 | 0.1 ± 0.10 | 0.415 | -0.3 ± 0.13 | 0.107 |
 Control | 4.4 ± 0.10 |  | 3.9 ± 0.09 |  | 3.8 ± 0.09 |  | -0.5 ± 0.09 | < 0.001 | -0.1 ± 0.08 | 0.702 | -0.6 ± 0.07 | < 0.001 |
 Difference | 0.1 ± 0.22 | 0.704 | 0.2 ± 0.24 | 0.410 | 0.4 ± 0.27 | 0.138 | 0.1 ± 0.14 | 0.428 | 0.2 ± 0.13 | 0.116 | 0.3 ± 0.14 | 0.029 |
Mean CBL | ||||||||||||
 Test | 3.6 ± 0.22 |  | 3.3 ± 0.18 |  | 3.5 ± 0.21 |  | -0.3 ± 0.28 | 0.611 | -0.1 ± 0.08 | 0.328 | -0.2 ± 0.30 | 0.881 |
 Control | 3.1 ± 0.20 |  | 3.0 ± 0.23 |  | 3.4 ± 0.27 |  | -0.1 ± 0.21 | 0.861 | 0.4 ± 0.21 | 0.186 | 0.3 ± 0.16 | 0.259 |
 Difference | 0.5 ± 0.46 | 0.320 | 0.3 ± 0.43 | 0.488 | -0.0 ± 0.52 | 0.960 | -0.2 ± 0.35 | 0.648 | -0.3 ± 0.22 | 0.222 | -0.4 ± 0.34 | 0.210 |
PCF | ||||||||||||
 Test | 89.5 ± 5.8 |  | 46.5 ± 5.2 |  | 51.1 ± 5.8 |  | -43.0 ± 4.6 |  < 0.001 | 4.6 ± 4.7 | 0.627 | -38.3 ± 6.7 | < 0.001 |
 Control | 76.3 ± 5.9 |  | 49.7 ± 6.0 |  | 55.7 ± 5.9 |  | -26.6 ± 6.4 | 0.002 | 6.0 ± 4.7 | 0.463 | -20.6 ± 4.9 | 0.002 |
 Difference | 13.1 ± 8.6 | 0.134 | -3.2 ± 9.2 | 0.727 | -4.6 ± 10.1 | 0.650 | -16.4 ± 7.8 | 0.042 | -1.4 ± 6.6 | 0.835 | -17.8 ± 8.2 | 0.037 |
 |  |  |  |  |  |  | OR0-6 |  | OR6-12 |  | OR0-12 |  |
Plaque (%) | ||||||||||||
 Test | 45.2 |  | 19.2 |  | 34.6 |  | 0.29 | 0.125 | 2.22 | 0.535 | 0.64 | 0.753 |
 Control | 54.8 |  | 38.7 |  | 45.2 |  | 0.52 | 0.554 | 1.30 | 0.927 | 0.68 | 0.763 |
 Odds ratio (OR) | 0.68 | 0.508 | 0.38 | 0.188 | 0.64 | 0.479 | 0.56 | 0.487 | 1.71 | 0.584 | 0.95 | 0.945 |
BoP (%) | ||||||||||||
 Test | 59.7 |  | 37.8 |  | 36.5 |  | 0.41 | < 0.001 | 0.95 | 0.947 | 0.39 | < 0.001 |
 Control | 58.1 |  | 32.3 |  | 32.3 |  | 0.34 | < 0.001 | 1.00 | 0.999 | 0.34 | < 0.001 |
 Odds ratio (OR) | 1.07 | 0.807 | 1.28 | 0.455 | 1.20 | 0.480 | 1.19 | 0.522 | 0.95 | 0.825 | 1.13 | 0.637 |
SUP (%) | ||||||||||||
 Test | 32.3 |  | 7.7 |  | 7.7 |  | 0.18 | 0.019 | 1.00 | 0.999 | 0.18 | 0.019 |
 Control | 16.7 |  | 6.5 |  | 6.5 |  | 0.34 | 0.210 | 1.00 | 0.999 | 0.34 | 0.210 |
 Odds ratio (OR) | 2.38 | 0.218 | 1.21 | 0.858 | 1.21 | 0.858 | 0.51 | 0.427 | 1.00 | 0.999 | 0.51 | 0.427 |