Fig. 2

NPRS score for each group before and after SRP therapy. ^**p < 0.01, ^***p < 0.001, ^****p < 0.0001 pre-SRP vs. post-SRP; ^$$$$p < 0.0001 vs. Periodontitis Stage I-II; two-way ANOVA followed by Sidak’s multiple comparisons test. ⁺⁺⁺p < 0.001, ⁺⁺⁺⁺p < 0.0001 vs. healthy group; one way ANOVA followed by Dunnett’s multiple comparisons test. Data are expressed as mean (SD). pre = pre-SRP, post = post-SRP, NPRS = numeric pain rating scale