Table 1 Materials utilized in this study their description, composition, manufacturer, and lot numbers

All Bond Universal

Ultra-mild Universal adhesive (pH > 3)

10-MDP, Bis-GMA, HEMA, Ethanol, Water, Initiators

Bisco, Schaumburg, Illinois, USA

2,100,006,253

Grandio

Universal nanohybrid resin composite.

Bis-GMA, TEDGMA, UDMA matrix.

87 wt% / 71.4 Vol.% inorganic filler loading.

VOCO GmbH, Cuxhaven, Germany

2,050,486

Meta Etchant

Etchant delivery

system

37% Phosphoric

Acid Semi Gel

META BIOMED CO.LTD., Korea

MET2009121

Han temp

Light curing temporary filling material.

UDMA,

HEMA,

Polyacrylic acid,

Silicon dioxide

HANDAE CHEMICAL CO., LTD, Korea

HT0762010

Theobromine

≥ 98.0%

Cocoa Extract

3,7-Dimethylxanthine,3,7-Dihydro-3,7-dimethyl-1 H-purine-2,6-dione, 2,6-Dihydroxy-3,7-dimethyl purine

Sigma Aldrich

BCBZ9934

MI paste plus

Topical Tooth Créme Containing Calcium, Phosphate & Fluoride

NaF (900 ppm F) 0.2% wt/vol, CPP-ACP 10% wt/vol

Water, Glycerol, D-sorbitol, CMC-Na, Propylene glycol, Silicon dioxide, Titanium dioxide, Xylitol, Phosphoric acid 75%,

Sodium saccharin, Flavor, Ethyl Para hydroxybenzoate, Propyl Para hydroxybenzoate, Butyl Para hydroxybenzoate

GC International,

USA

201112D