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Fig. 2 | BMC Oral Health

Fig. 2

From: The underlying molecular mechanisms and biomarkers between periodontitis and COVID-19

Fig. 2

Comparison of DEGs expression data between periodontitis and healthy individuals, and DEGs functional enrichment analysis. A Red dots and blue dots presented in volcano plots represent the significant DEGs of periodontitis, red dots represented up-regulated mRNA, blue dots represented down-regulated mRNA, in which some representative genes were highlighted with green dots. The criteria chosen to be considered as DEGs are (i) absolute value of log2 fold-change>1 (ii) adjusted P-value < 0.05. B Heatmap illustrating the top DEGs across periodontitis and healthy control; C Biological process-related GO terms identification results according to combined score. The higher the enrichment score, the higher number of genes are involved in a certain ontology; D Pathway analysis of DEGs between periodontitis and healthy control through KEGG

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