Fig. 3
From: The underlying molecular mechanisms and biomarkers between periodontitis and COVID-19
Comparison of DEGs expression data between COVID-19 and healthy individuals, and DEGs functional enrichment analysis. A Red dots and blue dots presented in volcano plots represent the significant DEGs of COVID-19, red dots represented up-regulated mRNA, blue dots represented down-regulated mRNA, in which some representative genes were highlighted with green dots. The criteria chosen to be considered as DEGs are (i) absolute value of log2 fold-change>1 (ii) adjusted P-value < 0.05. B Heatmap illustrating the top DEGs across COVID-19 and healthy control; C The bar graphs of ontological analysis of DEGs, for the biological process, immune effector process is among the top GO terms; D The bar graphs of KEGG pathway enrichment analysis of DEGs among COVID-19 and healthy control