Fig. 4
From: The underlying molecular mechanisms and biomarkers between periodontitis and COVID-19
A Enrichment of regulator shows NFE2 as the top-ranking TF; B Venn diagram showing 9 common up-regulated TFs across COVID-19 and periodontitis; C TFs-mRNA core network consists of the 175 pairs of mRNA and TFs among periodontitis and COVID-19, red circles indicate TFs, blue triangle indicate mRNAs, the edges between them mean that the mRNAs were potentially regulated by the TFs; TFs enrichment had been performed by Metascape tool. D Go enrichment showed that TFs was mainly involved in lymphocyte activation; (E) KEGG enrichment showed that TFs was involved in cancer related pathways