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Table 2 Analysis of microbiological variables in patients with hematologic malignancies or solid tumors and healthy subjects

From: Oral colonization by gram-negative bacilli in patients with hematologic malignancies and solid tumors compared with healthy controls

Characteristic

Hemato-oncologic patients

(N = 103)

n (%)

Healthy subjects

(N = 103)

n (%)

OR

95% CI

P value

Colonized by GNB

36 (34.9)

18 (17.5)

2.53 (1.32–4.86)

0.007 *

 Clinically relevant GNB isolated ‡

15 (14.5)

5 (4.8)

3.34 (1.16–9.56)

0.03 *

GNB isolated

    

 Klebsiella spp.

18 (17.5)

8 (7.8)

2.51 (1.04–6.07)

0.05 *

 Enterobacter spp.

3 (2.9)

5 (4.8)

0.58 (0.13–2.52)

0.72 †

 Citrobacter spp.

5 (4.8)

1 (0.9)

5.2 (0.59–45.34)

0.21 †

 Escherichia coli

5 (4.8)

1(0.9)

5.2 (0.59–45.34)

0.21 †

 Pseudomonas spp.

3 (2.9)

1(0.9)

3.06 (0.31–29.91)

0.62 †

 Stenotrophomonas maltophilia

1 (0.9)

2 (1.9)

0.49 (0.04–5.54)

1 †

 Acinetobacter sp.

1 (0.9)

0

-

1 †

Colonized by resistant GNB

12 (11.6)

0

28.3 (1.65-484.33)

< 0.001 *

Type of colonizing-resistant bacteria

 ESBL

2 (1.9)

-

-

-

 AmpC B-lactamase

2 (1.9)

-

-

-

 MDR

4 (3.8)

-

-

-

 MDR and ESBL

1 (0.9)

-

-

-

 Resistant to 1 antimicrobial group

3 (2.9)

-

-

-

  1. ESBL: extended spectrum β-lactamase; MDR: multidrug resistant; GNB: Gram-negative bacilli. OR: Odds ratio. CI: Confidence interval
  2. * Chi-square
  3. † Fisher’s exact test
  4. ‡ Clinically relevant GNB isolated: Citrobacter spp., Escherichia coli, Pseudomonas spp., Stenotrophomonas maltophilia, Acinetobacter spp.