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Table 3 Analysis of microbiological and hygienic-dietary variables as factors associated with oral colonization by GNB.

From: Oral colonization by gram-negative bacilli in patients with hematologic malignancies and solid tumors compared with healthy controls

Univariate analysis

Characteristic

Colonized by GNB

(N = 54)

n (%)

No colonized by GNB

(N = 152)

n (%)

OR

95% CI

P value

Group

    

 Hemato-oncologic patients

36 (67)

67 (44)

2.53 (1.32–4.86)

0.007 *

 Healthy subjects

18 (33)

85 (56)

Diagnosis

    

 No disease

18 (33)

85 (56)

0.39 (0.20–0.75)

0.007*

 Acute leukemias

6 (11)

16 (11)

1.06 (0.39–2.87)

0.88 *

 Lymphomas

8 (15)

12 (8)

2.02 (0.78–5.27)

0.22 *

 Multiple Myeloma

1 (2)

11 (7)

0.24 (0.03–1.91)

0.19 †

 Solid tumor

21 (39)

28 (18)

2.81 (1.42–5.58)

0.004 *

Charlson

    

 Low risk (0–2)

31 (57)

121 (80)

0.34 (0.17–0.67)

0.002*

 Intermediate risk (3–4)

11 (20)

11 (7)

3.27 (1.32–8.08)

0.01 *

 High risk (≥ 5)

12 (23)

20 (13)

1.88 (0.85–4.17)

0.17*

Visits to the dentist/year

    

 0 times

34 (63)

72 (47)

1.88 (0.99–3.57)

0.07*

 1 time

13 (24)

43 (28)

0.80 (0.39–1.64)

0.67*

 2 times

5 (9)

14 (9)

1.00 (0.34–2.93)

1.0 †

 ≥ 3 times

2 (4)

23 (15)

0.21 (0.04–0.94)

0.04*

Tooth brushing/day

    

 0 times

6 (11)

7 (5)

2.58 (0.82–8.08)

0.10 †

 1 time

12 (22)

24 (16)

1.52 (0.70–3.30)

0.38 *

 2 times

23 (43)

70 (46)

0.86 (0.46–1.62)

0.77*

 ≥3 times

13 (24)

51 (33)

0.62 (0.30–1.27)

0.26*

Flossing

10 (18)

42 (27)

0.59 (0.27–1.28)

0.25 *

Mouthwash use

6 (11)

37 (24)

0.38 (0.15–0.98)

0.039 *

Oral disease

10 (18)

25 (16)

1.15 (0.51–2.59)

0.88 *

Presence of caries

36 (67)

90 (59)

1.37 (0.71–2.64)

0.42 *

Dental treatment

8 (15)

36 (23)

0.56 (0.24–1.29)

0.24 *

Smoking

8 (15)

27 (17)

0.80 (0.34–1.89)

0.77 *

  1. GNB: Gram-negative bacilli. OR: Odds ratio. CI: Confidence interval
  2. * Chi-square
  3. † Fisher’s exact test