Diagnostic potential of miR-200 family members in gingival crevicular fluid for chronic periodontitis: correlation with clinical parameters and therapeutic implications

Table 1 Demographic and clinical characteristics of study participants

Characteristics	Chronic periodontitis (n = 103)	Healthy controls (n = 113)	P
Age	46 (40 ~ 53)	45 (37 ~ 53)	0.530
Gender
Male	50	62
Female	53	51	0.414
Education level
Primary school	43	44
High school	40	47
University	20	22	0.902
Body mass index (kg/m²)	20.9 (19.2 ~ 22.2)	21.1 (19.7 ~ 22.85)	0.123
Fasting glucose (mg/dL)	83.7 (80.6 ~ 87.1)	83.2 (80.05 ~ 86.1)	0.286
Smoking status
Never smokers	90	91
Past smokers	10	15
Current smokers	3	7	0.342
Ferritin (ng/mL)	150.3 (92.3 ~ 216.8)	151.6 (98.0 ~ 219.1)	0.430
hs-CRP (mg/dL)	0.390 (0.190 ~ 0.620)	0.270 (0.155 ~ 0.375)	< 0.001
CAL (mm)	4.8 (3.6 ~ 5.8)	1.6 (0.7 ~ 2.4)	< 0.001
PPD (mm)	4.9 (2.9 ~ 6.8)	1.9 (1.3 ~ 2.45)	< 0.001
PI	1.5 (1.1 ~ 1.7)	0.5 (0.3 ~ 0.7)	< 0.001
GI	1.4 (1.1 ~ 1.7)	0.5 (0.3 ~ 0.75)	< 0.001
BOP (%)	19.3 (11.6 ~ 25.8)	4.9 (2.65 ~ 7.5)	< 0.001

Note: hs-CRP = high-sensitivity C-reactive protein, PI = plaque index, PD = Probing Pocket Depth, CAL = clinical attachment level, GI (Gingival Index), BOP (Bleeding on Probing, %). All continuous values were presented as median ± interquartile range (IQR)

ISSN: 1472-6831