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Table 3 Univariate and multivariate logistic regression analyses to assess associated factors with the level of Candida.

From: Presence of Candida and its associated factors in participants attending oral cancer screening in the lower northeastern area of Thailand

Variable

Candida

High levels

Low levels

(n = 411)

High levels

(n = 166)

n (%)

n (%)

OR (unadjusted)

(95% CI)

p value

OR (adjusted)

(95% CI)

p value

Age (years)

      

 40–60

145 (84.8)

26 (15.2)

1

 

1

 

 61–69

143 (72.6)

54 (27.4)

2.11 (1.25–3.55)

0.05

1.87 (1.06–3.30)

0.03*

 ≥ 70

123 (58.9)

86 (41.1)

3.90 (2.40–6.43)

< 0.001*

2.65 (1.52–4.62)

< 0.001*

Gender

      

 Male

168 (89.4)

20 (10.6)

1

 

1

 

 Female

243 (62.5)

146 (37.5)

5.05 (3.04–8.38)

< 0.001*

2.62 (1.47–4.65)

< 0.001*

Smoking status

      

 Non-smoker

321 (67.2)

157 (32.8)

1

 

1

 

 Current smoker

90 (90.9)

9 (9.1)

0.20 (0.10–0.42)

< 0.001*

0.72 (0.31–1.65)

0.439

Use of smokeless tobacco

      

 Non-user

366 (72.2)

141 (27.8)

1

 

1

 

 Current user

45 (64.3)

25 (35.7)

1.44 (0.85–2.44)

0.171

1.40 (0.73–2.68)

0.311

Alcohol consumption

      

 Non-drinker

317 (68.5)

146 (31.5)

1

 

1

 

 Current alcohol drinker

94 (82.5)

20 (17.5)

0.46 (0.27–0.78)

0.03*

1.05 (0.55–1.98)

0.891

Betel quid chewing habit

      

 Non-chewer

315 (82.0)

69 (18.0)

1

 

1

 

 Current chewer

96 (49.7)

97 (50.3)

4.62 (3.14–6.77)

< 0.001*

2.82 (1.77–4.51)

< 0.001*

Working in the fields with strong sunlight

      

 No

172 (63.9)

97 (36.1)

1

 

1

 

 Yes

239 (77.6)

69 (22.4)

0.51 (0.36–0.74)

< 0.001*

0.86 (0.56–1.31)

0.476

Having irritation in the oral cavity

      

 No

325 (72.7)

122 (27.3)

1

 

1

 

 Yes

86 (66.2)

44 (33.8)

1.36 (0.90–2.07)

0.146

1.22 (0.71–2.07)

0.473

History of medical illness

      

 No

185 (74.6)

63 (25.4)

1

 

1

 

 Yes

226 (68.7)

103 (31.3)

1.34 (0.93–1.94)

0.121

1.48 (0.93–2.36)

0.102

Diabetes mellitus

      

 No

328 (71.3)

132 (28.7)

1

 

1

 

 Yes

83 (70.9)

34 (29.1)

1.02 (0.65–1.59)

0.938

0.77 (0.47–1.27)

0.312

Use of denture

      

 No

364 (71.9)

142 (28.1)

1

 

1

 

 Yes

47 (66.2)

24 (33.8)

1.31 (0.77–2.22)

0.317

1.96 (1.07–3.61)

0.03*

Xerostomia

      

 No

241 (73.9)

85 (26.1)

1

 

1

 

 Yes

170 (67.7)

81 (32.3)

1.35 (0.94–1.94)

0.103

1.24 (0.81–1.91)

0.319

Hyposalivation (< 0.7 ml/min)

      

 No

183 (83.2)

37 (16.8)

1

 

1

 

 Yes

228 (63.9)

129 (36.1)

2.80 (1.85–4.23)

< 0.001*

2.27 (1.44–3.60)

< 0.001*

Clinical diagnosis

      

 NOM

102 (77.3)

30 (22.7)

1

 

1

 

 OPMDs/OC

113 (68.5)

52 (31.5)

1.57 (0.93–2.64)

0.093

1.08 (0.60–1.96)

0.803

 Non-OPMDs/OC

155 (79.1)

41 (20.9)

0.90 (0.53–1.53)

0.697

0.96 (0.53–1.74)

0.893

 CSOC

41 (48.8)

43 (51.2)

3.57 (1.98–6.43)

< 0.001*

2.69 (1.39–5.22)

0.003*

  1. *Bold values denote statistical significance at the p < 0.05 level.
  2. *Adjust for age, gender, smoking, alcohol consumption, betel quid chewing, exposure to sunlight, irritation, medical history, diabetes mellitus, use of denture, xerostomia, hyposalivation and clinical diagnosis.