Table 5 Diagnostic performance parameters of CVMS for the diagnosis of MPSMS

Sensitivity (95%CI)

0.77 (0.64–0.86)

0.37 (0.25–0.51)

0.95 (0.89–0.98)

Specificity (95%CI)

0.94 (0.89–0.97)

0.95 (0.91–0.98)

0.88 (0.81–0.93)

AUC (95%CI)

0.85 (0.80–0.90)

0.66 (0.60–0.72)

0.91 (0.87–0.95)

Positive likelihood ratio (95%CI)

12.17 (6.58–22.52)

7.64 (3.60–16.22)

7.79 (4.84–12.54)

Negative likelihood ratio (95%CI)

0.25 (0.16–0.39)

0.66 (0.54–0.81)

0.06 (0.02–0.13)

Positive predictive value (95%CI)

0.83 (0.73–0.90)

0.73 (0.56–0.85)

0.86 (0.80–0.91)

Negative predictive value (95%CI)

0.91 (0.86–0.94)

0.81 (0.78–0.84)

0.96 (0.90–0.98)