Fig. 10
From: Identification of a novel PTH1R variant in a family with primary failure of eruption
A, the distribution of PPR exons and the position of c.1325-1336del. The normal sequence and corresponding amino acid sequence of the gene are in the left corner. The red part shows the missing segment. B, the 3D structure of PPR which contain 7 segments ofαhelices embedded between the lipid bilayer. The variant occurs in the red transmembrane region indicated by the black box. C, the specific location of the variant on the helix and the green globules represent the missing amino acids