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Table 3 Subgroup analysis of the association between H. pylori infection and Periodontal diseases occurrence by type of study based, population, methods of sampling and detect

From: The association between periodontal diseases and helicobacter pylori: an updated meta-analysis of observational studies

Variables

Subgroups

Number of study

Pooled Odds Ratio (95% CI)

Between Studies

Between Subgroup

I square (%)

P heterogeneity

Q

Q

P value

Type of study based

Hospital Based

18

2.64 (1.94–3.59)

43.98

0.05

30.29

0.42

0.59

Community Based

7

2.29 (1.71–3.07)

66.41

0.03

14.25

Population

General Population

4

1.94 (1.49–2.54)

54.65

0.09

6.43

3.87

0.43

Chronic Periodontal

15

2.57 (1.93–3.43)

36.07

0.07

22.34

Gastric Patients

6

3.49 (1.89–6.44)

56.76

0.05

11.84

 H. pylori detection

Polymerase Chain Reaction (PCR)

13

2.47 (1.66–3.67)

48.01

0.04

22.14

2.65

0.27

Rapid Urease Test

10

2.80 (2.18–3.60)

22.85

0.14

13.43

Other (Serology or ELIZA)

2

1.74 (1.04–2.92)

83.09

0.02

5.92

Continents

Asia

19

2.60 (2.05–3.31)

47.43

0.01

37.22

4.11

0.13

America

4

2.72 (1.45–5.25)

68.14

0.06

7.28

Europe

2

1.14 (0.53–1.47)

0.00

0.47

0.53

Periodontal Disease detection

CPITN

1

1.29 (0.45–3.66)

0.00

-

0.00

28.55

0.00

Index of Greene and Vermillion

1

2.10 (1.03–4.28)

0.00

-

0.00

Not reported

6

3.59 (2.51–5.13)

0.00

0.62

3.54

Oral examination

3

4.90 (2.81–8.52)

49.35

0.14

3.95

Probing test and clinical attachment loss

8

1.43 (1.13–1.82)

76.78

0.00

30.14

Probing test, Plaque index, Bleeding index

2

2.57 (1.36–4.85)

0.00

0.96

0.00

Clinical attachment loss

Not Reported

13

3.17 (2.46–4.09)

42.70

0.09

14.98

26.75

0.00

Attachment loss (mm)

2

3.04 (1.81–5.08)

0.00

0.57

0.32

> 4 mm

2

1.24 (0.86–1.79)

0.00

0.45

0.44

> 3 mm

4

1.27 (0.87–1.85)

24.76

0.29

9.17

Pocket status

Not Reported

10

3.19 (2.43–4.18)

46.98

0.04

9.07

21.41

0.00

Pocket depth (mm)

2

3.04 (1.81–5.08)

0.00

0.32

0.75

> 5

2

1.54 (0.79–3.03)

0.00

0.48

0.50

> 3

3

1.29 (0.81–2.05)

79.88

0.00

14.99

> 4

4

1.44 (1.05–1.98)

12.73

3.44

0.33