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Table 2 Characteristics of the included studies. M: Morelli; OO: Ortho Organizers; AO: American Orthodontics; OT: Ortho Technology (USA); 3 M: 3 M Unitek; OP: Ortho Plus; D: Dentaurum (Alemania); RMO: Rocky Mountain; P: pre-stretched; SP: without pre-stretched

From: Effect of mouthwashes on the force decay of polymeric ligature chains used for dental purposes: a systematic review and meta-analysis

AUTHOR

STUDY DESIGN

SAMPLE

CHAIN

LINKS

MANUFACTURER

DISTANCE BETWEEN PINS

TIME

TYPE OF MOUTHWASH/AGENT

CONTROL GROUP

MOUTHWASH APPLICATION

RESULTS

QUALITY

Al – Ani [13]

In vitro

72

short

-

M

29 mm

0 h, 24 h, 7d, 21d

Listerine®- Zero (without alcohol)

Listerine® Original (26,9% alcohol)

Distilled water

60 seg / 12 h

All groups with alcohol showed an increase in strength loss compared to the non-alcoholic and distilled water control group (p < 0.05).

MEDIUM

Menon et al. [11]

In vitro

840

short

3

OO

23,5 mm

0 h, 24 h, 7, 14, 21, 28 d.

Listerine®; Colgate Phos Flur®,

Clorhex Plus®; 26,9% alcohol;

0.04% NaF; Clorhexidine 0,2%

Artificial saliva

60 seg / 12 h

At 24 h, the greatest loss of strength (49.48%) was observed in the 26.9% Alcohol group in the short elastomeric chains. The best result was obtained by 0.2% chlorhexidine with a loss of 46.7% (p < 0.5)

LOW

Behnaz et al. [17]

In vitro

160

short

6

AO

25 mm

0 h, 24 h, 7, 14, 21, 28 d.

Listerine® Total Care Zero

Listerine® Healthy White

Artificial saliva

30 seg / 12 h

At 24 h the greatest loss of decomposition of the elastomeric chains was produced in all the groups. In the control group, the loss of strength was 42.18%, while in daily mouth rinses with whitening agents it was 48.34% (Listerine ® Total Care Zero) and 53.38% (Listerine ® Healthy White) respectively (p < 0.05)

LOW

Nahidh et al. [20]

In vitro

440

short

-

OT

29 mm

0 h, 24 h, 7, 14, 21, 28 d.

Listerine® green tea.

(Camellia Sinensis Green tea; NaF)

Tebodont

(Melaleuca Alternifolia, tea tree oil)

Aloe - dent

(aloe vera, peppermint oil, mentol, Melaleuca Alternifolia)

Herba Silca

(Milenrama, chamomile, calendula, salvia)

Distilled water

60 seg / 12 h

They found the greatest degradation of strength in the control group at 24 h of 52%. There were no statistically significant differences with the herbal rinses (p < 0.05)

LOW

Ramachandraiah et al. [19]

In vitro

180

corta

3

3 M; OP; OO

18 mm (P).

22 mm (SP).

0 h, 24 h, 7, 14, 21, 28 d.

Listerine®; Wokadine;

Alcohol 21,6%; Alcohol 8,38%

Artificial saliva

60 seg / 12 h

In all groups, including the control group, the greatest loss of strength was obtained at 24 h in the group of elastomeric chains without pre-stretching compared to the pre-stretched chains that obtained better results.

LOW

Mirhashemi et al. [4]

In vitro

315

Sin enlace

-

AO

24 mm

0 h, 24 h, 7, 14, 21, 28 d.

Persica; Clorhexidine 0,2%

Sodium Fluorure 0,2%; CLX + Sodium Fluorure

Artificial saliva

60 seg / 12 h

A loss of strength was observed with statistically significant results for all groups (p < 0.001). The greatest strength degradation occurred at 24 h in the CLX + NaF group.

MEDIUM

Sadeghian et al. [14]

In vitro

90

short

5

AO; D

25 mm

0 h, 24 h, 7, 14, 21, 28 d.

Sodium Fluorure 0,05%;

Listerine®

Artificial saliva

60 seg / 24 h

The results showed that the effect of the commercial house on the strength of the elastomeric chains was statistically significant and that the average strength of the AO chains was higher than that of the Dentaurum house (p = 0.001). Both NaF and Listerine ® intensified the loss of strength of the elastomeric chains (p < 0.001)

LOW

Javanmardi and Salehi [3]

In vitro

80

short

5

OT

15 mm

0 h, 24 h, 7, 14, 21, 28 d.

Orthokin®; Sensikin®;

Persica

Artificial saliva

60 seg / 12 h

The highest percentage of strength degradation was in the Persica group. The Orthokin® mouthwash was the one that obtained the best results compared to the other groups, including the control group.

LOW

Omidkhoda et al. [16]

In vitro

120

short/ closed

5/7

D

25 mm

0 h, 24 h, 7, 14, 21, 28 d.

Clorhexidine 0,2%; Persica

Sodio Fluorure 0,05%

Artificial saliva

60 seg / 24 h

Chlorhexidine caused the greatest loss of strength at 24 h (27.24% in closed connectors) followed by NaF and artificial saliva. Persica obtained the best results.

LOW

Oshagh et al. [18]

In vitro

-

closed

4

OT

25 mm

0 h, 24 h, 7, 14, 21, 28 d.

Sodium Fluorure 0,0%

Clorhexidine 0,2%; Té

Distilled water

60 seg / 24 h

The greatest loss of strength was observed at 24 h in all groups, but there were no statistically significant differences in terms of strength degradation with the different mouthwashes (p < 0.05).

LOW

Kumar et al. [12]

In vitro

480

short

4

3 M

25 mm

0 h, 24 h, 7, 14, 21, 28 d.

Coca-Cola; Listerine®

Tea

Distilled water

60 seg / 12 h

Tea caused the greatest degradation of strength followed by the Listerine ® and Coca-Cola group compared to the control group with statistically significant results (p < 0.01)

LOW

Pithon et al. [15]

In vitro

90

short

5

M

23,5 mm

0 h, 24 h, 7, 14, 21, 28 d.

Clorhexidine 0,12%; Clorhexidine 0,2%

Periogard® 0,12%; Cleanform®

Distilled water

30 seg / 12 h

Chlorhexidine did not show a statistically significant influence on the pattern of degradation of the strength of the elastomeric chains (p < 0.05).

LOW

Pithon et al. [7]

In vitro

108

short

5

M

23,5 mm

0 h, 24 h, 7, 14, 21, 28 d.

Plax; Listerine®

Plax Whitening; Listerine® Whitening

Distilled water

60 seg / 12 h

All groups obtained the greatest loss of strength at 24 h. After 28 days, the greatest loss of strength occurred in the control group (artificial saliva). The presence of bleaching agent had no relevance in the results obtained.

LOW

Larrabee et al. [8]

In vitro

450

short

3

RMO

23,5 mm

0 h, 24 h, 7, 14, 21, 28 d.

Alcohol 14%; Alcohol 26,9%

Cepacol® (alcohol 14%); Listerine® (alcohol 26,9%)

Distilled water

60 seg / 12 h

Cepacol® mouthwash obtained 54.2% loss of strength at 24 h compared to 53% for Listerine®. All alcohol groups caused an increase in the disintegration force of the elastomeric chains with time.

LOW