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Table 6 Management of medical treatment and the complications of invasive procedures for patients taking biologics

From: Management of dental care of patients on immunosuppressive drugs for chronic immune-related inflammatory diseases: a survey of French dentists’ practices

 

All practitioners

N = 104 (%)a

Specialized dentist activityb

N = 47 (%)

General dentist activity

N = 5 7 (%)

 

Complications after mucoperiosteal flap rising with bone resection/curetting

No

Yes

p-value

No

Yes

p-value

No

Yes

p-value

Preoperative management of the medical treatment

 No modification

35 (33.65)

4 (3.85)

0.04

14 (29.78)

4 (8.51)

0.04

21 (36.84)

0 (0.00)

-

 Discontinuation (different protocols)

64 (61.53)

1 (0.96)

28 (59.57)

1 (2.13)

36 (63.16)

0 (0.00)

Pre, per, and postoperative dental-care protocol

Antiseptic mouthwash

  Never

10 (9.62)

0 (0.00)

0.45

5 (10.64)

0 (0.00)

0.41

5 (8.77)

0 (0.00)

-

  Ever (pre, per, and/or postoperative)

89 (85.57)

5 (4.81)

37 (78.72)

5 (10.64)

52 (91.23)

0 (0.00)

Antibiotics

  Never

6 (5.77)

0 (0.00)

0.84

1 (2.13)

0 (0.00)

0.89

5 (8.77)

0 (0.00)

-

  Exclusively single dose preoperatively

16 (15.38)

1 (0.96)

6 (12.77)

1 (2.13)

10 (17.54)

0 (0.00)

  Antibiotic coverage/both single dose preoperatively and antibiotic coverage

77 (74.04)

4 (3.85)

 

35 (74.47)

4 (8.51)

 

42 (73.69)

0 (0.00)

 
 

Dry socket

No

Yes

p-value

No

Yes

p-value

No

Yes

p-value

Preoperative management of the medical treatment

 No modification

33 (31.73)

6 (5.76)

0.12

13 (27.66)

5 (10.64)

0.05

20 (35.09)

1 (1.75)

0.89

 Discontinuation (different protocols)

61 (58.65)

4 (3.85)

27 (57.44)

2 (4.26)

34 (59.65)

2 (3.51)

Pre, per, and postoperative dental-care protocol

Antiseptic mouthwash

  Never

10 (9.62)

0 (0.00)

0.27

5 (10.64)

0 (0.00)

0.32

5 (8.77)

0 (0.00)

0.58

  Ever (pre, per, and/or postoperative)

84 (80.76)

10 (9.62)

35 (74.47)

7 (14.89)

49 (85.97)

3 (5.26)

Antibiotics

  Never

6 (5.77)

0 (0.00)

0.37

1 (2.13)

0 (0.00)

0.07

5 (8.77)

0 (0.00)

0.56

  Exclusively single dose preoperatively

14 (13.46)

3 (2.88)

4 (8.51)

3 (6.39)

10 (17.54)

0 (0.00)

  Antibiotic coverage/both single dose preoperatively and antibiotic coverage

74 (71.15)

7 (6.73)

 

35 (74.47)

4 (8.51)

 

39 (68.43)

3 (5.26)

 
  1. aOnly practitioners who responded that they are concerned about the care of patients taking biologics (n = 104) were included in this analysis
  2. bSpecialized activity: oral surgery, periodontology, endodontics, pediatric dentistry