Table 1 Randomized trials reporting treatment of periodontal intrabony defects
Author (year) | Study Design, Blinded (duration) | Population | Intervention (number of surgical sites) | ||||
|---|---|---|---|---|---|---|---|
No. of participants (sites) | Age (mean/range) | gender | Control (sites) | Test (sites) | |||
Qiao et al. (2016) [64] | Split-mouth and Parallel, examiner-blinded (12 months) | 17 (31) | 47.7 ± 13.9 (24–64) | 7 M/10F | OFD + BO (16) | OFD + BO + CGF (15) | |
Xu et al. (2019) [66] | Parallel, examiner-blinded (12 months) | 54 (120) | 55.2 ± 8.3 (N) | 32 M/26F | OFD (30) | T1: OFD + CGF (30); T2: OFD + BO (30); T3: OFD + BO + CGF (30) | |
Samarth et al. (2023) [69] | Split-mouth, examiner-blinded (12 months) | 10 (60) | N (30–60) | 3 M/7F | OFD + DFDBA (30) | T: OFD + DFDBA + CGF membrane (30) | |